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Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia

An on-demand anesthetic that would only take effect when needed and where the intensity of anesthesia could be easily adjustable according to patients’ needs would be highly desirable. Here, we design and synthesize a macromolecular prodrug (P407-CM-T) in which the local anesthetic tetracaine (T) is...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Zhang, Wei, Ji, Tianjiao, Li, Yang, Zheng, Yueqin, Mehta, Manisha, Zhao, Chao, Liu, Andong, Kohane, Daniel S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210304/
https://ncbi.nlm.nih.gov/pubmed/32385252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16177-w
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