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A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle

The expression of N-glycolylneuraminic acid (Neu5Gc) and the cytotoxic T cell (CT) carbohydrate can impact the severity of muscular dystrophy arising from the loss of dystrophin in mdx mice. Here, we describe the expression of these two glycans in skeletal muscles of dogs and humans with or without...

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Autors principals: Martin, Paul T., Golden, Bethannie, Okerblom, Jonathan, Camboni, Marybeth, Chandrasekharan, Kumaran, Xu, Rui, Varki, Ajit, Flanigan, Kevin M., Kornegay, Joe N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914967/
https://ncbi.nlm.nih.gov/pubmed/24505439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088226
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