A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle

The expression of N-glycolylneuraminic acid (Neu5Gc) and the cytotoxic T cell (CT) carbohydrate can impact the severity of muscular dystrophy arising from the loss of dystrophin in mdx mice. Here, we describe the expression of these two glycans in skeletal muscles of dogs and humans with or without...

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Detalhes bibliográficos
Main Authors: Martin, Paul T., Golden, Bethannie, Okerblom, Jonathan, Camboni, Marybeth, Chandrasekharan, Kumaran, Xu, Rui, Varki, Ajit, Flanigan, Kevin M., Kornegay, Joe N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914967/
https://ncbi.nlm.nih.gov/pubmed/24505439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088226
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