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Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model
The t(8;21) chromosomal translocation activates aberrant expression of the AML1-ETO (AE) fusion protein and is commonly associated with core binding factor acute myeloid leukaemia (CBF AML). Combining a conditional mouse model that closely resembles the slow evolution and the mosaic AE expression pa...
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Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
John Wiley and Sons
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914523/ https://ncbi.nlm.nih.gov/pubmed/24124051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302661 |
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