Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression

BACKGROUND: Conditional gene activation is an efficient strategy for studying gene function in genetically modified animals. Among the presently available gene switches, the tetracycline-regulated system has attracted considerable interest because of its unique potential for reversible and adjustabl...

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Main Authors: Wörtge, Simone, Eshkind, Leonid, Cabezas-Wallscheid, Nina, Lakaye, Bernard, Kim, Jinhyun, Heck, Rosario, Abassi, Yasmin, Diken, Mustafa, Sprengel, Rolf, Bockamp, Ernesto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944160/
https://ncbi.nlm.nih.gov/pubmed/20815887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-95
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