Llwytho...
Efficient Gene Knock-out and Knock-in with Transgenic Cas9 in Drosophila
Bacterial Cas9 nuclease induces site-specific DNA breaks using small gRNA as guides. Cas9 has been successfully introduced into Drosophila for genome editing. Here, we improve the versatility of this method by developing a transgenic system that expresses Cas9 in the Drosophila germline. Using this...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Genetics Society of America
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025491/ https://ncbi.nlm.nih.gov/pubmed/24657904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.010496 |
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