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Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines

Treatments for lymphomas include gemcitabine (Gem) and clofarabine (Clo) which inhibit DNA synthesis. To improve their cytotoxicity, we studied their synergism with the alkyl phospholipid edelfosine (Ed). Exposure of the J45.01 and SUP-T1 (T-cell) and the OCI-LY10 (B-cell) lymphoma cell lines to IC(...

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Detalhes bibliográficos
Main Authors: Valdez, B C, Zander, A R, Song, G, Murray, D, Nieto, Y, Li, Y, Champlin, R E, Andersson, B S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913938/
https://ncbi.nlm.nih.gov/pubmed/24413065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2013.69
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