The synergistic cytotoxicity of clofarabine, fludarabine and busulfan in AML cells involves ATM pathway activation and chromatin remodeling

DNA alkylating agents alone or with ionizing radiation have been the preferred conditioning treatment in allogeneic hematopoietic stem cell transplantation (allo-HSCT). In search of less toxic alternatives, we hypothesized that combination of busulfan (Bu), fludarabine (Flu) and clofarabine (Clo) wo...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Valdez, Benigno C., Li, Yang, Murray, David, Champlin, Richard E., Andersson, Borje S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006064/
https://ncbi.nlm.nih.gov/pubmed/20933509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.09.027
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