Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: enhancement of cytotoxicity with epigenetic modulators

Clofarabine (Clo), fludarabine (Flu) and busulfan (Bu) combinations are efficacious in hematopoietic stem cell transplantation (HSCT) for myeloid leukemia. We now determined if the more affordable drug cladribine (Clad) can provide a viable alternative to Clo, with or without panobinostat (Pano) and...

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Detalhes bibliográficos
Publicado no:Exp Hematol
Main Authors: Valdez, Benigno C., Li, Yang, Murray, David, Ji, Jie, Liu, Yan, Popat, Uday, Champlin, Richard E., Andersson, Borje S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458397/
https://ncbi.nlm.nih.gov/pubmed/25704054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.02.001
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