Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: enhancement of cytotoxicity with epigenetic modulators

Clofarabine (Clo), fludarabine (Flu) and busulfan (Bu) combinations are efficacious in hematopoietic stem cell transplantation (HSCT) for myeloid leukemia. We now determined if the more affordable drug cladribine (Clad) can provide a viable alternative to Clo, with or without panobinostat (Pano) and...

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Bibliografische gegevens
Gepubliceerd in:Exp Hematol
Hoofdauteurs: Valdez, Benigno C., Li, Yang, Murray, David, Ji, Jie, Liu, Yan, Popat, Uday, Champlin, Richard E., Andersson, Borje S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458397/
https://ncbi.nlm.nih.gov/pubmed/25704054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.02.001
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