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Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines

Treatments for lymphomas include gemcitabine (Gem) and clofarabine (Clo) which inhibit DNA synthesis. To improve their cytotoxicity, we studied their synergism with the alkyl phospholipid edelfosine (Ed). Exposure of the J45.01 and SUP-T1 (T-cell) and the OCI-LY10 (B-cell) lymphoma cell lines to IC(...

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Dettagli Bibliografici
Autori principali: Valdez, B C, Zander, A R, Song, G, Murray, D, Nieto, Y, Li, Y, Champlin, R E, Andersson, B S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913938/
https://ncbi.nlm.nih.gov/pubmed/24413065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2013.69
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