Mechanistic studies on the synergistic cytotoxicity of the nucleoside analogs gemcitabine and clofarabine in multiple myeloma: Relevance of p53 and its clinical implications

Hematopoietic stem cell transplantation (HSCT) is an established treatment for multiple myeloma (MM), a plasma cell malignancy. To identify an improved pretransplant conditioning regimen, we investigated the cytotoxicity of gemcitabine (Gem) and clofarabine (Clo) combinations toward MM cell lines an...

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Main Authors: Valdez, Benigno C., Wang, Guiyun, Murray, David, Nieto, Yago, Li, Yang, Shah, Jatin, Turturro, Francesco, Wang, Michael, Weber, Donna M., Champlin, Richard E., Qazilbash, Muzaffar H., Andersson, Borje S.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769691/
https://ncbi.nlm.nih.gov/pubmed/23648290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.04.009
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