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Synergistic cytotoxicity of sorafenib with busulfan and nucleoside analogs in human FLT3-ITD-positive acute myeloid leukemia cells
Clofarabine (Clo), fludarabine (Flu), and busulfan (Bu) are used in pre-transplant conditioning therapy for patients with myeloid leukemia. To further improve their efficacy in FLT3-ITD-positive AML, we investigated their synergism with sorafenib (Sor). Exposure of FLT3-ITD-positive MV-4-11 and MOLM...
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| Publicado no: | Biol Blood Marrow Transplant |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5002996/ https://ncbi.nlm.nih.gov/pubmed/25111583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2014.08.003 |
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