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The histone deacetylase inhibitor SAHA sensitizes acute myeloid leukemia cells to a combination of nucleoside analogs and the DNA-alkylating agent busulfan
Fludarabine (Flu), clofarabine (Clo) and busulfan (Bu) are used in allogeneic hematopoietic stem cell transplant (allo-HSCT). We reported that combining [Flu + Clo + Bu] had a synergistic cytotoxicity in AML cells. We hypothesized that combining [Flu + Clo + Bu] with the histone deacetylase inhibito...
Shranjeno v:
izdano v: | Leuk Lymphoma |
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Main Authors: | , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320642/ https://ncbi.nlm.nih.gov/pubmed/24144307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.856007 |
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