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Panobinostat and venetoclax enhance the cytotoxicity of gemcitabine, busulfan, and melphalan in multiple myeloma cells

Gemcitabine (Gem), busulfan (Bu) and melphalan (Mel) are used for hematopoietic stem cell transplantation (HSCT). To further improve their efficacy, a preclinical study on their synergism with the HDAC inhibitor panobinostat (Pano) and the BCL2 inhibitor venetoclax/ABT199 was performed. Multiple mye...

詳細記述

保存先:
書誌詳細
出版年:Exp Hematol
主要な著者: Valdez, Benigno C., Li, Yang, Murray, David, Liu, Yan, Nieto, Yago, Bashir, Qaiser, Qazilbash, Muzaffar H., Andersson, Borje S.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023992/
https://ncbi.nlm.nih.gov/pubmed/31954171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.01.003
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