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Panobinostat and venetoclax enhance the cytotoxicity of gemcitabine, busulfan, and melphalan in multiple myeloma cells
Gemcitabine (Gem), busulfan (Bu) and melphalan (Mel) are used for hematopoietic stem cell transplantation (HSCT). To further improve their efficacy, a preclinical study on their synergism with the HDAC inhibitor panobinostat (Pano) and the BCL2 inhibitor venetoclax/ABT199 was performed. Multiple mye...
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| Publicado no: | Exp Hematol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7023992/ https://ncbi.nlm.nih.gov/pubmed/31954171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.01.003 |
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