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Sidedness of Carbamazepine Accessibility to Voltage-Gated Sodium Channels

Voltage-gated sodium channels are inhibited by many local anesthetics, antiarrhythmics, and antiepileptic drugs. The local anesthetic lidocaine appears to be able to access its binding site in the sodium channel only from the membrane phase or from the internal face of the channel. In contrast, the...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jo, Sooyeon, Bean, Bruce P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913360/
https://ncbi.nlm.nih.gov/pubmed/24319110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.090472
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