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Sidedness of Carbamazepine Accessibility to Voltage-Gated Sodium Channels
Voltage-gated sodium channels are inhibited by many local anesthetics, antiarrhythmics, and antiepileptic drugs. The local anesthetic lidocaine appears to be able to access its binding site in the sodium channel only from the membrane phase or from the internal face of the channel. In contrast, the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3913360/ https://ncbi.nlm.nih.gov/pubmed/24319110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.090472 |
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