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Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction

The unexpected connection between cilia and signaling is one of the most exciting developments in cell biology in the past decade. In particular, the Hedgehog (Hh) signaling pathway relies on the primary cilium to regulate tissue patterning and homeostasis in vertebrates. A central question is how c...

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Detalhes bibliográficos
Main Authors: Nozawa, Yoko Inès, Lin, Chuwen, Chuang, Pao-Tien
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913210/
https://ncbi.nlm.nih.gov/pubmed/23725801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2013.04.008
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