Llwytho...
Smoothened Adopts Multiple Active and Inactive Conformations Capable of Trafficking to the Primary Cilium
Activation of Hedgehog (Hh) signaling requires the transmembrane protein Smoothened (Smo), a member of the G-protein coupled receptor superfamily. In mammals, Smo translocates to the primary cilium upon binding of Hh ligands to their receptor, Patched (Ptch1), but it is unclear if ciliary traffickin...
Wedi'i Gadw mewn:
| Prif Awduron: | , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Public Library of Science
2009
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664476/ https://ncbi.nlm.nih.gov/pubmed/19365551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005182 |
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