Multiple productive immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukemia are mostly derived from independent clones

In chronic lymphocytic leukemia, usually a monoclonal disease, multiple productive immunoglobulin heavy chain gene rearrangements are identified sporadically. Prognostication of such cases based on immunoglobulin heavy variable gene mutational status can be problematic, especially if the different r...

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Main Authors: Plevova, Karla, Francova, Hana Skuhrova, Burckova, Katerina, Brychtova, Yvona, Doubek, Michael, Pavlova, Sarka, Malcikova, Jitka, Mayer, Jiri, Tichy, Boris, Pospisilova, Sarka
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2014
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912964/
https://ncbi.nlm.nih.gov/pubmed/24038023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.087593
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