Multiple productive immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukemia are mostly derived from independent clones

In chronic lymphocytic leukemia, usually a monoclonal disease, multiple productive immunoglobulin heavy chain gene rearrangements are identified sporadically. Prognostication of such cases based on immunoglobulin heavy variable gene mutational status can be problematic, especially if the different r...

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Hoofdauteurs: Plevova, Karla, Francova, Hana Skuhrova, Burckova, Katerina, Brychtova, Yvona, Doubek, Michael, Pavlova, Sarka, Malcikova, Jitka, Mayer, Jiri, Tichy, Boris, Pospisilova, Sarka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ferrata Storti Foundation 2014
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912964/
https://ncbi.nlm.nih.gov/pubmed/24038023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.087593
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