Dysregulation of the mTOR pathway in p53-deficient mice

Mammalian or mechanistic target of rapamycin (mTOR) is involved in growth, aging, and age-related diseases including cancer. There is an extensive cross talk between p53 and mTOR. In cell culture, p53 inhibits the mTOR pathway in a cell type-dependent manner. p53-deficient mice develop pro-inflammat...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Leontieva, Olga V, Novototskaya, Liliya R, Paszkiewicz, Geraldine M, Komarova, Elena A, Gudkov, Andrei V, Blagosklonny, Mikhail V
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912042/
https://ncbi.nlm.nih.gov/pubmed/24184801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.26947
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi