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Gerosuppression by pan-mTOR inhibitors
Rapamycin slows organismal aging and delays age-related diseases, extending lifespan in numerous species. In cells, rapamycin and other rapalogs such as everolimus suppress geroconversion from quiescence to senescence. Rapamycin inhibits some, but not all, activities of mTOR. Recently we and others...
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| Publicado en: | Aging (Albany NY) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5270685/ https://ncbi.nlm.nih.gov/pubmed/28077803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101155 |
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