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Gerosuppression by pan-mTOR inhibitors
Rapamycin slows organismal aging and delays age-related diseases, extending lifespan in numerous species. In cells, rapamycin and other rapalogs such as everolimus suppress geroconversion from quiescence to senescence. Rapamycin inhibits some, but not all, activities of mTOR. Recently we and others...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5270685/ https://ncbi.nlm.nih.gov/pubmed/28077803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101155 |
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