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Gerosuppression in confluent cells

The most physiological type of cell cycle arrest – namely, contact inhibition in dense culture - is the least densely studied. Despite cell cycle arrest, confluent cells do not become senescent. We recently described that mTOR (target of rapamycin) is inactive in contact-inhibited cells. Therefore,...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Leontieva, Olga V., Blagosklonny, Mikhail V.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298362/
https://ncbi.nlm.nih.gov/pubmed/25585637
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