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Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?
I discuss a very obscure activity of p53, namely suppression of senescence (gerosuppression), which is also manifested as anti-hypertrophic, anti-hypermetabolic, anti-inflammatory and anti-secretory effects of p53. But can gerossuppression suppress tumors?
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433931/ https://ncbi.nlm.nih.gov/pubmed/22869016 |
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