Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma

Granulocyte-macrophage colony-stimulating factor (GM-CSF) enhances immune responses by inducing dendritic cell proliferation, maturation, and migration and B and T lymphocyte expansion and differentiation. The potency of DNA vaccines can be enhanced by the addition of DNA encoding cytokines, acting...

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Detalhes bibliográficos
Main Authors: Perales, Miguel-Angel, Yuan, Jianda, Powel, Sarah, Gallardo, Humilidad F., Rasalan, Teresa S., Gonzalez, Christina, Manukian, Gregor, Wang, Jian, Zhang, Yan, Chapman, Paul B., Krown, Susan E., Livingston, Philip O., Ejadi, Samuel, Panageas, Katherine S., Engelhorn, Manuel E., Terzulli, Stephanie L., Houghton, Alan N., Wolchok, Jedd D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909666/
https://ncbi.nlm.nih.gov/pubmed/18797450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.196
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