A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events

Although recurrent somatic mutations in the splicing factor U2AF1 (also known as U2AF35) have been identified in multiple cancer types, the effects of these mutations on the cancer transcriptome have yet to be fully elucidated. Here, we identified splicing alterations associated with U2AF1 mutations...

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Detalhes bibliográficos
Main Authors: Brooks, Angela N., Choi, Peter S., de Waal, Luc, Sharifnia, Tanaz, Imielinski, Marcin, Saksena, Gordon, Pedamallu, Chandra Sekhar, Sivachenko, Andrey, Rosenberg, Mara, Chmielecki, Juliann, Lawrence, Michael S., DeLuca, David S., Getz, Gad, Meyerson, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909098/
https://ncbi.nlm.nih.gov/pubmed/24498085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087361
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