An In Silico Approach for Modelling T-Helper Polarizing iNKT Cell Agonists

Many analogues of the glycolipid alpha-galactosylceramide (α-GalCer) are known to activate iNKT cells through their interaction with CD1d-expressing antigen-presenting cells, inducing the release of Th1 and Th2 cytokines. Because of iNKT cell involvement and associated Th1/Th2 cytokine changes in a...

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Autori principali: De Spiegeleer, Anton, Wynendaele, Evelien, Vandekerckhove, Matthias, Stalmans, Sofie, Boucart, Maxime, Van Den Noortgate, Nele, Venken, Koen, Van Calenbergh, Serge, Aspeslagh, Sandrine, Elewaut, Dirk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909045/
https://ncbi.nlm.nih.gov/pubmed/24498010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087000
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