Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer

BACKGROUND: A major problem in cancer chemotherapy is the existence of primary resistance and/or the acquisition of secondary resistance. Many cellular defects contribute to chemoresistance, but epigenetic changes can also be a cause. METHODS: A DNA methylation microarray was used to identify epigen...

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Detalhes bibliográficos
Main Authors: Moutinho, Catia, Martinez-Cardús, Anna, Santos, Cristina, Navarro-Pérez, Valentin, Martínez-Balibrea, Eva, Musulen, Eva, Carmona, F. Javier, Sartore-Bianchi, Andrea, Cassingena, Andrea, Siena, Salvatore, Elez, Elena, Tabernero, Josep, Salazar, Ramon, Abad, Albert, Esteller, Manel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906989/
https://ncbi.nlm.nih.gov/pubmed/24273214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt322
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