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Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection
In G2 phase cells, DNA double-strand break repair switches from DNA non-homologous end-joining to homologous recombination. This switch demands the promotion of resection. We examine the changes in 53BP1 and RAP80 ionizing radiation induced foci (IRIF) in G2 phase, as these are factors that restrict...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905848/ https://ncbi.nlm.nih.gov/pubmed/24013561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt802 |
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