Opposing roles for 53BP1 during homologous recombination

Although DNA non-homologous end-joining repairs most DNA double-strand breaks (DSBs) in G2 phase, late repairing DSBs undergo resection and repair by homologous recombination (HR). Based on parallels to the situation in G1 cells, previous work has suggested that DSBs that undergo repair by HR predom...

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Bibliografiset tiedot
Päätekijät: Kakarougkas, Andreas, Ismail, Amani, Klement, Karolin, Goodarzi, Aaron A., Conrad, Sandro, Freire, Raimundo, Shibata, Atsushi, Lobrich, Markus, Jeggo, Penny A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
Aiheet:
Genome Integrity, Repair and Replication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834810/
https://ncbi.nlm.nih.gov/pubmed/23969417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt729
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