Pazopanib Enhances Paclitaxel-Induced Mitotic Catastrophe in Anaplastic Thyroid Cancer

Anaplastic thyroid cancer (ATC) has perhaps the worst prognosis of any cancer, with a median survival of only about 5 months regardless of stage. Pazopanib monotherapy has promising clinical activity in differentiated thyroid cancers (generally attributed to vascular endothelial growth factor recept...

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Autori principali: Isham, Crescent R., Bossou, Ayoko R., Negron, Vivian, Fisher, Kelly E., Kumar, Rakesh, Marlow, Laura, Lingle, Wilma L., Smallridge, Robert C., Sherman, Eric J., Suman, Vera J., Copland, John A., Bible, Keith C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905331/
https://ncbi.nlm.nih.gov/pubmed/23283368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3004358
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