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Pazopanib Enhances Paclitaxel-Induced Mitotic Catastrophe in Anaplastic Thyroid Cancer

Anaplastic thyroid cancer (ATC) has perhaps the worst prognosis of any cancer, with a median survival of only about 5 months regardless of stage. Pazopanib monotherapy has promising clinical activity in differentiated thyroid cancers (generally attributed to vascular endothelial growth factor recept...

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Hlavní autoři: Isham, Crescent R., Bossou, Ayoko R., Negron, Vivian, Fisher, Kelly E., Kumar, Rakesh, Marlow, Laura, Lingle, Wilma L., Smallridge, Robert C., Sherman, Eric J., Suman, Vera J., Copland, John A., Bible, Keith C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905331/
https://ncbi.nlm.nih.gov/pubmed/23283368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3004358
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