Pazopanib Enhances Paclitaxel-Induced Mitotic Catastrophe in Anaplastic Thyroid Cancer

Anaplastic thyroid cancer (ATC) has perhaps the worst prognosis of any cancer, with a median survival of only about 5 months regardless of stage. Pazopanib monotherapy has promising clinical activity in differentiated thyroid cancers (generally attributed to vascular endothelial growth factor recept...

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Main Authors: Isham, Crescent R., Bossou, Ayoko R., Negron, Vivian, Fisher, Kelly E., Kumar, Rakesh, Marlow, Laura, Lingle, Wilma L., Smallridge, Robert C., Sherman, Eric J., Suman, Vera J., Copland, John A., Bible, Keith C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905331/
https://ncbi.nlm.nih.gov/pubmed/23283368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3004358
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