Co-delivery of paclitaxel and cetuximab by nanodiamond enhances mitotic catastrophe and tumor inhibition

The poor intracellular uptake and non-specific binding of anticancer drugs into cancer cells are the bottlenecks in cancer therapy. Nanocarrier platforms provide the opportunities to improve the drug efficacy. Here we show a carbon-based nanomaterial nanodiamond (ND) that carried paclitaxel (PTX), a...

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Udgivet i:Sci Rep
Main Authors: Lin, Yu-Wei, Raj, Emmanuel Naveen, Liao, Wei-Siang, Lin, Johnson, Liu, Kuang-Kai, Chen, Ting-Hua, Cheng, Hsiao-Chun, Wang, Chi-Ching, Li, Lily Yi, Chen, Chinpiao, Chao, Jui-I
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575327/
https://ncbi.nlm.nih.gov/pubmed/28852020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09983-8
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