Reduced migration of MLH1 deficient colon cancer cells depends on SPTAN1

INTRODUCTION: Defects in the DNA mismatch repair (MMR) protein MLH1 are frequently observed in sporadic and hereditary colorectal cancers (CRC). Affected tumors generate much less metastatic potential than the MLH1 proficient forms. Although MLH1 has been shown to be not only involved in postreplica...

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Detaylı Bibliyografya
Asıl Yazarlar: Hinrichsen, Inga, Ernst, Benjamin Philipp, Nuber, Franziska, Passmann, Sandra, Schäfer, Dieter, Steinke, Verena, Friedrichs, Nicolaus, Plotz, Guido, Zeuzem, Stefan, Brieger, Angela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904401/
https://ncbi.nlm.nih.gov/pubmed/24456667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-11
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