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C-Terminal Fluorescent Labeling Impairs Functionality of DNA Mismatch Repair Proteins
The human DNA mismatch repair (MMR) process is crucial to maintain the integrity of the genome and requires many different proteins which interact perfectly and coordinated. Germline mutations in MMR genes are responsible for the development of the hereditary form of colorectal cancer called Lynch s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3279419/ https://ncbi.nlm.nih.gov/pubmed/22348133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031863 |
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