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Orexin/hypocretin receptor signalling: a functional perspective
Multiple homeostatic systems are regulated by orexin (hypocretin) peptides and their two known GPCRs. Activation of orexin receptors promotes waking and is essential for expression of normal sleep and waking behaviour, with the sleep disorder narcolepsy resulting from the absence of orexin signallin...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The British Pharmacological Society
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904253/ https://ncbi.nlm.nih.gov/pubmed/23848055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12296 |
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