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Orexin/hypocretin receptor signalling: a functional perspective

Multiple homeostatic systems are regulated by orexin (hypocretin) peptides and their two known GPCRs. Activation of orexin receptors promotes waking and is essential for expression of normal sleep and waking behaviour, with the sleep disorder narcolepsy resulting from the absence of orexin signallin...

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Détails bibliographiques
Auteurs principaux: Leonard, C S, Kukkonen, J P
Format: Artigo
Langue:Inglês
Publié: The British Pharmacological Society 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904253/
https://ncbi.nlm.nih.gov/pubmed/23848055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12296
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