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Orexin/hypocretin receptor signalling cascades

Orexin (hypocretin) peptides and their two known G-protein-coupled receptors play essential roles in sleep–wake control and powerfully influence other systems regulating appetite/metabolism, stress and reward. Consequently, drugs that influence signalling by these receptors may provide novel therape...

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Autori principali: Kukkonen, JP, Leonard, CS
Natura: Artigo
Lingua:Inglês
Pubblicazione: The British Pharmacological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904254/
https://ncbi.nlm.nih.gov/pubmed/23902572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12324
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