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Calcium affects OX(1) orexin (hypocretin) receptor responses by modifying both orexin binding and the signal transduction machinery

BACKGROUND AND PURPOSE: One of the major responses upon orexin receptor activation is Ca(2+) influx, and this influx seems to amplify the other responses mediated by orexin receptors. However, the reduction in Ca(2+), often used to assess the importance of Ca(2+) influx, might affect other propertie...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Putula, Jaana, Pihlajamaa, Tero, Kukkonen, Jyrki P
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290719/
https://ncbi.nlm.nih.gov/pubmed/25132134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12883
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