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Discovery of potent parthenolide-based antileukemic agents enabled by late-stage P450-mediated C—H functionalization
The sesquiterpene lactone parthenolide has recently attracted considerable attention owing to its promising antitumor properties, in particular in the context of stem-cell cancers including leukemia. Yet, the lack of viable synthetic routes for reelaborating this complex natural product have represe...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904131/ https://ncbi.nlm.nih.gov/pubmed/24206617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400626w |
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