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Anticancer activity profiling of parthenolide analogs generated via P450-mediated chemoenzymatic synthesis
The plant-derived sesquiterpene lactone parthenolide (PTL) was recently found to possess promising anticancer activity but elaboration of this natural product scaffold for optimization of its pharmacological properties has proven challenging via available chemical methods. In this work, P450-catalyz...
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| 出版年: | Bioorg Med Chem |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803483/ https://ncbi.nlm.nih.gov/pubmed/28826596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.08.009 |
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