Stabilization of the Reductase Domain in the Catalytically Self-Sufficient Cytochrome P450(BM3) by Consensus-Guided Mutagenesis

The multidomain, catalytically self-sufficient cytochrome P450 BM-3 from Bacillus megaterium (P450(BM3)) constitutes a versatile enzyme for the oxyfunctionalization of organic molecules and natural products. However, the limited stability of the diflavin reductase domain limits the utility of this e...

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Vydáno v:Chembiochem
Hlavní autoři: Saab-Rincón, Gloria, Alwaseem, Hanan, Guzmán-Luna, Valeria, Olvera, Leticia, Fasan, Rudi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941085/
https://ncbi.nlm.nih.gov/pubmed/29276819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700546
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