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Stabilization of the Reductase Domain in the Catalytically Self-Sufficient Cytochrome P450(BM3) by Consensus-Guided Mutagenesis
The multidomain, catalytically self-sufficient cytochrome P450 BM-3 from Bacillus megaterium (P450(BM3)) constitutes a versatile enzyme for the oxyfunctionalization of organic molecules and natural products. However, the limited stability of the diflavin reductase domain limits the utility of this e...
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| Опубликовано в: : | Chembiochem |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5941085/ https://ncbi.nlm.nih.gov/pubmed/29276819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700546 |
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