Targeted mutation of Ncam to produce a secreted molecule results in a dominant embryonic lethality.
The neural cell adhesion molecule (NCAM) is a membrane-associated member of the immunoglobulin superfamily capable of both homophilic and heterophilic binding. To investigate the significance of this binding, a gene targeting strategy in embryonic stem (ES) cells was used to replace the membrane-ass...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1996
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39038/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692830/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6421 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|