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Interaction of p53 with the human Rad51 protein.

p53 is thought to function in the maintenance of genomic stability by modulating transcription and interacting with cellular proteins to influence the cell cycle, DNA repair and apoptosis. p53 mutations occur in >50% of human cancers, and cells which lack wild type p53 accumulate karyotypic abnor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Buchhop, S, Gibson, M K, Wang, X W, Wagner, P, Stürzbecher, H W, Harris, C C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC146972/
https://ncbi.nlm.nih.gov/pubmed/9380510
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