Mismatch repair protein hMSH2–hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediate

High fidelity homologous DNA recombination depends on mismatch repair (MMR), which antagonizes recombination between divergent sequences by rejecting heteroduplex DNA containing excessive nucleotide mismatches. The hMSH2–hMSH6 heterodimer is the first responder in postreplicative MMR and also plays...

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Detalhes bibliográficos
Principais autores: Honda, Masayoshi, Okuno, Yusuke, Hengel, Sarah R., Martín-López, Juana V., Cook, Christopher P., Amunugama, Ravindra, Soukup, Randal J., Subramanyam, Shyamal, Fishel, Richard, Spies, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903253/
https://ncbi.nlm.nih.gov/pubmed/24395779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312988111
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