Mismatch repair protein hMSH2–hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediate

High fidelity homologous DNA recombination depends on mismatch repair (MMR), which antagonizes recombination between divergent sequences by rejecting heteroduplex DNA containing excessive nucleotide mismatches. The hMSH2–hMSH6 heterodimer is the first responder in postreplicative MMR and also plays...

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Bibliografiske detaljer
Main Authors: Honda, Masayoshi, Okuno, Yusuke, Hengel, Sarah R., Martín-López, Juana V., Cook, Christopher P., Amunugama, Ravindra, Soukup, Randal J., Subramanyam, Shyamal, Fishel, Richard, Spies, Maria
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903253/
https://ncbi.nlm.nih.gov/pubmed/24395779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312988111
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